BDBM318716 (4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[4- (ethylsulfonyl)-1,4-diazepan-1-yl]-4- pyridin-2-yl-4,5-dihydroimidazo[1,5,4- de][1,4]benzoxazine::US10464947, Example 248::US11498926, Example 248::US9624241, Example 248

SMILES CCS(=O)(=O)N1CCCN(CC1)c1nc2ccc(-c3c(C)noc3C)c3OC[C@H](c4ccccn4)n1c23

InChI Key InChIKey=VYGHZNPCDJGFSN-JOCHJYFZSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318716   

TargetBromodomain-containing protein 4 [353-454](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM318716((4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[4- (ethylsul...)
Affinity DataIC50: <100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent